Background: Smoking has been consistently linked with delayed bone healing and increased postoperative complications. The comparison of fracture healing between smokers and non-smokers can provide crucial insights for better patient management. Aim: To compare the healing time of fractures in smokers vs. nonsmokers and evaluate associated risk factors influencing recovery. Methods: A prospective observational study was conducted on 100 patients with long bone fractures. Patients were grouped into smokers (n=50) and non-smokers (n=50). Radiological evidence of callus formation and clinical signs of union were assessed. Healing time, complications, and functional recovery were analyzed. Results: The average fracture healing time in smokers was 16–20 weeks, compared to 10–14 weeks in non-smokers. The rate of delayed union and non-union was significantly higher among smokers (28%) than non-smokers (6%). Functional outcomes were poorer in smokers. Conclusion: Smoking significantly delays fracture healing and increases postoperative complications. Smoking cessation should be strongly recommended to all fracture patients.